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Aspects of HIV and HCV


HIV
HCV
Blood-borne & sexually transmitted virus Blood-borne
Affects the immune system Affects the liver
Infection is lifelong Appox. 15-25% clear the virus
75-85% develop chronic infection
IDU is a major risk factor IDU is a major risk factor
NO vaccine available NO vaccine available
ELISA/EIA screening with RIBA or PCR
confirmation
ELISA/EIA screening with Western Blot
confirmation
Treatment may last a lifetime Treatment typically lasts 6 – 12 months
High viral load indicates disease progression High viral load does not correlate with liver damage
Viral loads do not randomly fluctuate Viral loads fluctuate randomly
Many anti-viral treatments available Only interferon and ribavirin approved at this time
Appears to accelerate HCV progression Unclear if HCV accelerates HIV progression
High risk of transmission from blood to blood
contact
Rate of transmission from blood to blood contact is
10 times higher than HIV
Transmission by unprotected sex Lower chance of unprotected sexual transmission
Mother to infant transmission 20 – 30% Mother to infant transmission 4%


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